Scientific Papers

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2015
0

Thirst driving and suppressing signals encoded by distinct neural populations in the brain

Scientific papers, Thirst

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Thirst is the basic instinct to drink water. Previously, it was shown that neurons in several circumventricular organs of the hypothalamus are activated by thirst-inducing conditions. Here we identify two distinct, genetically separable neural populations in the subfornical organ that trigger or suppress thirst. We show that optogenetic activation of subfornical organ excitatory neurons, marked […]

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2015
0

Sauna-induced body mass loss in young sedentary women and men

Environmental conditions, Scientific papers, Sweat and sweating

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The aim of the study was to evaluate the relationship between body mass index (BMI) and body mass loss (BML) induced by thermal stress in a dry sauna. The study was conducted on a group of 674 sedentary students, 326 women and 348 men aged 19-20. The correlations between BMI scores and BML were determined. […]

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2015
0

Sonographic inferior vena cava measurements to assess hydration status in college football players during preseason cAMP

Exercise and sport, Scientific papers

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OBJECTIVES: The purpose of this study was to determine whether sonographic measurement of the inferior vena cava (IVC) in college football players during preseason camp is a reliable way to detect and monitor dehydration. Our primary hypothesis was that IVC diameter measurements, the postpractice caval index, and expiratory diameter were significantly related to percent weight […]

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2015
0

24-h Void number as an indicator of hydration status

Hydration status: effects on physiology and metabolism, Scientific papers

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Background/Objectives:Few user-friendly hydration assessment techniques exist for the general population to use on a daily basis. The present study evaluated void number over 24 h as a potential hydration assessment tool.Subjects/Methods:Male and female subjects collected urine for 24 h while adequately hydrated (n=44; 22±4 years, 168±16 cm, 73±15 kg) or fluid restricted (n=43; 22±3 years, 175±10 cm, 81±24 kg). As a […]

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2015
0

Oral hydration for prevention of contrast-induced acute kidney injury in elective radiological procedures: a systematic review and meta-analysis of randomized controlled trials

Renal function, Scientific papers

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BACKGROUND: The reports on efficacy of oral hydration treatment for the prevention of contrast-induced acute kidney injury (CIAKI) in elective radiological procedures and cardiac catheterization remain controversial. AIMS:The objective of this meta-analysis was to assess the use of oral hydration regimen for prevention of CIAKI. MATERIALS AND METHODS:Comprehensive literature searches for randomized controlled trials (RCTs) […]

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2015
0

Patients admitted to hospital from care homes are at higher risk of dehydration, study finds

Clinical care, Hydration status of population groups, Scientific papers

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OBJECTIVE: To compare risks of hypernatraemia on admission to hospital in persons who were with those who were not identified as care home residents and evaluate the association of hypernatraemia with in-hospital mortality. DESIGN: Retrospective observational study. SETTING: A National Health Service Trust in London. PARTICIPANTS: A total of 21,610 patients aged over 65 years […]

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2015
0

Are patients admitted to hospitals from care homes dehydrated? A retrospective analysis of hypernatraemia and in-hospital mortality

Clinical care, Hydration status of population groups, Scientific papers

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OBJECTIVE: To compare risks of hypernatraemia on admission to hospital in persons who were with those who were not identified as care home residents and evaluate the association of hypernatraemia with in-hospital mortality. DESIGN: Retrospective observational study. SETTING: A National Health Service Trust in London. PARTICIPANTS:A total of 21,610 patients aged over 65 years whose […]

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2015
0

Disentangling Volumetric and Hydrational Properties of Proteins

Hydration status: effects on physiology and metabolism, Scientific papers

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We used molecular dynamics simulations of a typical monomeric protein, SNase, in combination with Voronoi-Delaunay tessellation to study and analyze the temperature dependence of the apparent volume, Vapp, of the solute. We show that the void volume, VB, created in the boundary region between solute and solvent, determines the temperature dependence of Vapp to a […]

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2015
0

Manipulations to the Alcohol and Sodium Content of Beer for Post Exercise Rehydration

Exercise and sport, Regulation of water and electrolyte balance, Renal function, Scientific papers

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The addition of 25 mmol·L-1 sodium to low alcohol (2.3% ABV) beer has been shown to enhance post exercise fluid retention compared to full strength (4.8% ABV) beer with and without electrolyte modification. This investigation explored the effect of further manipulations to the alcohol and sodium content of beer on fluid restoration following exercise. Twelve […]

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2015
0

Exercise-associated hyponatremic encephalopathy and exertional heatstroke in a soldier: high rates of fluid intake during exercise caused rather than prevented a fatal outcome

Electrolytes, hyponatraemia, Environmental conditions, Exercise and sport, Scientific papers

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Athletes are often advised to drink in order to “fully replace bodyweight losses” in order to prevent exertional heatstroke (EHS) during exercise in the heat. There is little evidence that “dehydration” in the range experienced by athletes adversely affects thermoregulation or is the exclusive cause of EHS. In contrast it is established that excess fluid […]

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